Dr TANG, Qianyuan, 唐乾元博士
Assistant Professor
B.Sc., Ph.D., Nanjing University, Nanjing, China.
Postdoctoral, University of Tokyo, Tokyo, Japan.
Research Scientist, RIKEN Center for Brain Sciences, Wako, Japan.
Current Research Interests
Dr. Tang's research leverages advanced computational and data-driven approaches to simplify complex biological systems and uncover the universal laws governing their behaviours. His interdisciplinary research program draws on computational, statistical, and mathematical techniques to analyze complex biological data. By utilizing large datasets and AI-based methods, Dr. Tang aims to better understand the underlying mechanisms of diseases and develop new treatments to improve human health. His research interests include:
2. AI for biomedical sciences
3. Protein evolution and dynamics
4. Complexity and criticality of biological systems
More information can be found at https://sites.google.com/view/tangqy/
Selected Publications
Xingyue Guan, Qian-Yuan Tang, Weitong Ren, Mingchen Chen, Wei Wang, Peter G. Wolynes, Wenfei Li, Predicting protein conformational motions using energetic frustration analysis and AlphaFold2. Proceedings of the National Academy of Sciences. 121 (35) e2410662121 (2024). https://doi.org/10.1073/pnas.2410662121
Zeke Xie, Qian-Yuan Tang, Mingming Sun, Ping Li, On the Overlooked Structure of Stochastic Gradients, Proceedings of the 37th International Conference on Neural Information Processing Systems (NeurIPS 2023), pp. 66257-66276. (2023) https://dl.acm.org/doi/10.5555/3666122.3669014.
- Qian-Yuan Tang, Weitong Ren, Jun Wang, Kunihiko Kaneko, The Statistical Trends of Protein Evolution: A Lesson from AlphaFold Database. Molecular Biology and Evolution, 39(10), msac197 (2022). https://doi.org/10.1093/molbev/msac197
- Qian-Yuan Tang, Kunihiko Kaneko. Dynamics-Evolution Correspondence of Protein Structures. Physical Review Letters, 127, 098103 (2021). https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.127.098103
- Qian-Yuan Tang, Testsuhiro S. Hatakeyama, Kunihiko Kaneko, Functional Sensitivity and Mutational Robustness of Proteins, Physical Review Research, 2(3), 033452 (2020). https://journals.aps.org/prresearch/abstract/10.1103/PhysRevResearch.2.033452
- Qian-Yuan Tang, Kunihiko Kaneko. Long-range correlation in protein dynamics: Confirmation by structural data and normal mode analysis. PLoS Computational Biology, 16(2), e1007670 (2020). https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007670
- Qian-Yuan Tang, Yang-Yang Zhang, Jun Wang, Wei Wang, and Dante R. Chialvo, Critical fluctuations in the native state of proteins, Physical Review Letters, 118, 088102 (2017). https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.118.088102