Center for Quantitative Systems Biology

CAI, Zongwei

Contact: Rm. T1214, Hong Kong Baptist University
Tel: (852) 3411-7070

Professor Cai graduated from Xiamen University in 1982 with a B.Sc. degree and University of Marburg , Germany in 1990 with a Ph.D. degree. He worked in University of Nebraska, USA as a post-doc. from 1991-93; assistant director of mass spectrometry center from 1993-96 and research assistant professor from 1994-96. From 1996-2000, Dr. Cai worked in a major pharmaceutical company (Glaxo-Wellcome) and lead a mass spectrometry group to support drug metabolism and pharmacokinetic study. He is now a Professor and Chair in Department of Chemistry, Hong Kong Baptist University, and also serves as the Director of Dioxin Laboratory. Dr. Cai was awarded for National Science Fund for Distinguished Young Scholar (Oversea, Hong Kong and Macao) by National Nature Science Foundation of China in 2003 and "Min Jiang Scholar - Chair Professor" in 2007..

Current Research Interests

Selected Publications

1. Mutations in influenza virus replication and transcription: Detection of amino acid substitutions in hemagglutinin of an avian influenza virus (H1N1), Ning Liu, Genyan Huang, Yi Guan, Kimchung Lee, Honglin Chen8, Zongwei Cai, The FASEB Journal, 2009, 23, 3377-3382.
2. Analysis of Adenosine Phosphates in HepG-2 Cell by a HPLC-ESI-MS System with Porous Graphitic Carbon as Stationary Phase, Jun Wang, Tao Lin, Jiaping Lai, M.S. Yang, Zongwei Cai, J. Chromatogr. B 877 (2009) 2019-2024.
3. A Method to Enhance a1 Ions and Application for Peptide Sequencing and Protein Identification, Ning Liu, Wan Chan, Kim-Chung Lee, Zongwei Cai, J Am Soc Mass Spectrom 2009, 20, 1214-1223.
4. Identification of Amino Acid Substitutions in Mutated Peptides of Nucleoprotein from Avian Influenza Virus, Ning Liu, Kim-Chung Lee, Wenjun Song, Pui Wang, Zongwei Cai, Honglin Chen, Talanta, 78 (2009) 1492-1496.
5. A new approach for the sensitive determination of DNA adduct of aristolochic acid II by using high-performance liquid chromatography with fluorescence detection, Wan Chan, Wing Tat Poon, Yan-Wo Chan, King-Yi Wan, Zongwei Cai, Journal of Chromatography B, 877 (2009) 848-852.
6. "Combination of Ł]-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites", Yufang Zheng, Zhihong Guo, Zongwei Cai, Talanta 78 (2009) 358-363.
7. Identification of Four Urea Adducts of Andrographolide in Humans, Liang Cui, Wan Chan, Feng Qiu, Zongwei Cai and Xinsheng Yao* Drug Metabolism Letters, 2008, 2, 1-8.
8. Identification of Amino Acid Substitutions in Avian Influenza Virus (H5N1) Matrix Protein by Using Nanoelectrospray MS and MS/MS, Ning Liu, Wenjun Song, Kim-Chung Lee, Pui Wang, Honglin Chen, Zongwei Cai, J Am Soc Mass Spectrom 2009, 20, 312-320.
9. Quantification of aristolochic acid-derived DNA adducts in rat kidney and liver by using liquid chromatography-electrospray ionization mass spectrometry, Wan Chan, Hao Yue, Wing Tat Poon, Yan-Wo Chan, Oliver J. Schmitz, Daniel W.J. Kwong, Ricky N.S. Wong, Zongwei Cai , Mutation Res. 2008, 646, 17-24 (IF. 4.159)
10. Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells, Ting Lei, Qing-Yu He, Zhen Cai, Yuan Zhou, Yi-LiWang, Lu-Sheng Si, Zongwei Cai, Jen-Fu Chiu, Proteomics 2008, 8, 2420-2429.