Professor Xiangze Zeng Receives HK$1.65 Million NSFC Grant for Investigating Phase Separation in DNA Damage Repair 

Professor Xiangze Zeng Receives HK$1.65 Million NSFC Grant for Investigating Phase Separation in DNA Damage Repair 

We are delighted to share that Professor Xiangze Zeng (Department of Physics, HKBU) has been awarded a prestigious grant of approximately HK$1.65 million under the National Key Research and Development Program for Young Scientists. This collaborative research project (total funding: HK$5.55 million) aims to elucidate molecular mechanisms governing the formation and pathological phase transitions of biomolecular condensates during DNA damage repair process, paving the way for novel disease intervention and treatment.

As co-principal investigator, Prof. Zeng is collaborating with distinguished scholars, Prof. Miao Yu (PC) and Prof Ming Luo (co-PI) from Wuhan University and Prof. Xiaojie Zhang (co-PI) from ShanghaiTech University. Leveraging his expertise in computational biophysics, Prof. Zeng’s group will use multiscale modeling to provide atomic-level insights into these cellular processes. His work will complement the team's advanced experimental techniques, including super-resolution microscopy, cryo-electron tomography and clinical studies, creating a powerful, synergistic approach to unlock the secrets of DNA damage repair.