Dr XIE, Tingting

I have extensive experience in molecular biomarker research within liquid biopsy applications for clinical diagnostics, particularly focused on cancer detection in both urine and plasma samples. My work centers on advancing novel methodologies for analyzing fragmented DNA in biofluids, aiming to enhance the sensitivity and specificity of early cancer detection.

1. Tingting Xie, Guangya Wang, Spencer C Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W Y Chan, Ze Zhou, Mary-Jane L Ma, Diana S C Han, Jeremy Y C Teoh, W K Jacky Lam, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Y M Dennis Lo (2022) High-resolution analysis for urinary DNA jagged ends. NPJ Genome Medicine. 2022 Feb 23;7(1):14.
2. Tingting Xie,, Margaret C.W. Ho, Qili Liu, Chun-Chieh Lin, Wakako Horiuchi, Haojiang Luan, Benjamin H. White, Christopher J. Potter, and Mark N Wu (2018) A genetic toolkit for dissecting dopamine circuit function in Drosophila. Cell Reports. 23, 652-665.
3. Peiyong Jiang, Tingting Xie, Spencer C. Ding, Ze Zhou, Suk Hang Cheng, Rebecca W.Y. Chan, Wing-Shan Lee, Wenlei Peng, John Wong, Vincent W.S. Wong, Henry L.Y. Chan, Stephen L. Chan, Liona C.Y. Poon, Tak Y. Leung, K.C. Allen Chan, Rossa W.K. Chiu, and Y.M. Dennis Lo (2020) Jagged ends of double-stranded DNA in plasma: detection, characterization and diagnostic applications. Genome Research. 30(8):1144-1153. (co-first)
4. Peiyong Jiang, Kun Sun, Wenlei Peng, Suk Hang Cheng, Meng Ni, Philip Yeung, Macy Heung, Tingting Xie, Huimin Shang, Ze Zhou, Rebecca Chan, John Wong, Vincent Wong, Liona Poon, Tak Yeung Leung, W.K. Lam, Jason Ying Kuen Chan, Henry LY Chan, KC Allen Chan, Rossa Chiu, and Y. M. Dennis Lo (2020) Plasma DNA end motifprofiling as a fragmentomic marker in cancer, pregnancy and transplantation. Cancer Discovery. 2020 Feb 28. pii: CD-19-0622.
5. Ze Zhou, Suk Hang Cheng, Spencer C. Ding, Macy M. S. Heung, Tingting Xie, Timothy HT Cheng, Wai Kei Jacky Lam, Wenlei Peng, Jeremy Y.C. Teoh, Peter Ka-Fung Chiu, Chi Fai Ng, Peiyong Jiang, K.C. Allen Chan, Rossa W.K. Chiu, and Y.M. Dennis Lo (2021) Jagged ends of urinary cell-free DNA: characterization and feasibility assessment in bladder cancer detection Clinical Chemistry. 2021 Feb 19: havv325.